Thionyl Chloride → 3-Methyl-6-(phenylthio)-benzyl chloride

HRID 435665노트

반응식

HRID 435665 반응식
[CH3:1][C:2]1[CH:3]=[C:4]([C:7]([S:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[CH:8][CH:9]=1)[CH2:5]O.S(Cl)([Cl:19])=O>C1C=CC=CC=1>[CH3:1][C:2]1[CH:3]=[C:4]([C:7]([S:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[CH:8][CH:9]=1)[CH2:5][Cl:19]

참가 물질

4

반응물 2

HCID 24386Thionyl ChlorideHCID 12539099HCID 12539099, 화합물

생성물 1

HCID 125391003-Methyl-6-(phenylthio)-benzyl chloride

시약·촉매·용매 1

HCID 241Benzene용매

실험 절차

570.7 g of 3-methyl-6-(phenylthio)-benzyl alcohol are dissolved in 1.5 litres of benzene and heated under reflux. There are added dropwise thereto within 45 minutes 352 ml of thionyl chloride and the mixture is boiled for a further 90 minutes. Then the mixture is concentrated under reduced pressure and there is obtained 3-methyl-6-(phenylthio)-benzyl chloride as a red-brown oil.

후처리

  1. temperatureheated
  2. temperatureunder reflux
  3. additionThere are added dropwise
  4. concentrationThen the mixture is concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-5c9ac29b07614bd8afa424a4ace031fa
출처 데이터셋
uspto-grants-1977_02
특허 번호
US04006144

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