Thionyl Chloride → HCID 15619001, 화합물
반응식
[C:1]1([S:7][C:8]2[CH:15]=[CH:14][C:13]([C:16]([F:19])([F:18])[F:17])=[CH:12][C:9]=2[CH2:10]O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.S(Cl)([Cl:22])=O>C1C=CC=CC=1>[C:1]1([S:7][C:8]2[CH:15]=[CH:14][C:13]([C:16]([F:19])([F:18])[F:17])=[CH:12][C:9]=2[CH2:10][Cl:22])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1참가 물질
4
실험 절차
96 g of 2-(phenylthio)-5-trifluoromethyl-benzyl alcohol are dissolved in 450 ml of absolute benzene and heated to reflux. The solution thus obtained is treated dropwise over a period of 20 minutes with 48 ml of thionyl chloride and the mixture is subsequently stirred at reflux for 30 minutes. After cooling, the mixture is evaporated under reduced pressure. There is obtained 2-(phenylthio)-5-trifluoromethyl-benzyl chloride as a brown-yellow oil.
후처리
- temperatureheated to reflux
- customThe solution thus obtained
- temperatureat reflux for 30 minutes
- temperatureAfter cooling
- customthe mixture is evaporated under reduced pressure
출처 및 근거
- ORD 기록
- ord-3b912a9eb34546278b7e28fe7a7b6651
- 출처 데이터셋
- uspto-grants-1977_02
- 특허 번호
- US04006144
반응 노트
불러오는 중…