Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 2-(Hydroxymethyl)-7-methoxy-9H-xanthen-9-OL
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Sulfuric acid magnesium salt (1:1) | HCID 24083 | — |
| 반응물 | Aluminium lithium hydride | HCID 21226445 | — |
| 반응물 | Ethyl 7-methoxy-9-oxoxanthene-2-carboxylate | HCID 21455094 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 2-(Hydroxymethyl)-7-methoxy-9H-xanthen-9-OL | HCID 21455095 | 84% |
반응 단계
Lithium aluminum hydride (500 mg) was added to a stirred solution of ethyl 7-methoxy-9-oxoxanthene-2-carboxylate (1g) in THF (100 ml). The reaction mixture was stirred at room temperature under nitrogen for 5 hours. Water and MgSO4 were added. The inorganic solids were filtered off and washed with ethyl acetate. The filtrate and washings were combined and evaporated to give the crude product. Recrystallization from ethyl acetate gave white crystals (0.82 g, 84%), mp. 142°-143°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04007205 |
| 출처 데이터셋 | uspto-grants-1977_02 |
| ORD ID | ord-67a38b1b31974630bd45356f0540d6db |
| 출처 메모 | uspto-grants-1977_02 |