Sodium Iodide → (E)-1-Iodo-1-octen-3-one

HRID 436093

반응식

HRID 436093 반응식
[I-:1].[Na+].Cl/[CH:4]=[CH:5]/[C:6](=[O:12])[CH2:7][CH2:8][CH2:9][CH2:10][CH3:11]>CC(C)=O>[I:1]/[CH:4]=[CH:5]/[C:6](=[O:12])[CH2:7][CH2:8][CH2:9][CH2:10][CH3:11]

참가 물질

4

반응물 2

HCID 5238Sodium IodideHCID 110410031-Chloro-trans-1-octen-3-one

생성물 1

HCID 11139597(E)-1-Iodo-1-octen-3-one

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

A mixture of 54.5 g. (0.364 mole) of sodium iodide and 40 g. (0.249 mole) of 1-chloro-trans-1-octen 3-one (Example 723) in 360 ml. of acetone is stirred and refluxed for 24 hours. The reaction mixture is cooled, filtered and concentrated. The residue is partitioned between water and ether. The organic phase is washed with dilute sodium bicarbonate solution, brine, dried (MgSO4) and evaporated to an oil. This material is used directly without purification.

후처리

  1. additionA mixture of 54.5 g
  2. temperaturerefluxed for 24 hours
  3. temperatureThe reaction mixture is cooled
  4. filtrationfiltered
  5. concentrationconcentrated
  6. customThe residue is partitioned between water and ether
  7. washThe organic phase is washed with dilute sodium bicarbonate solution, brine
  8. dry with materialdried (MgSO4)
  9. customevaporated to an oil
  10. customThis material is used directly without purification

출처 및 근거

ORD 기록
ord-f019da7ee0374284afd756b21286e23b
출처 데이터셋
uspto-grants-1977_02
특허 번호
US04007210

연결된 노트

불러오는 중…