Methanol → 2-(4-Carbomethoxyphenyl)-2,4,5,6-tetrahydro-1,3,4,6,6-pentamethylcyclopenta[c]pyrrole-4-carboxamide

HRID 436325노트

반응식

HRID 436325 반응식
[C:1]([C:4]1[CH:9]=[CH:8][C:7]([N:10]2[C:14]([CH3:15])=[C:13]3[C:16]([CH3:24])([C:21]([NH2:23])=[O:22])[CH2:17][C:18]([CH3:20])([CH3:19])[C:12]3=[C:11]2[CH3:25])=[CH:6][CH:5]=1)([OH:3])=[O:2].[CH3:26]O>>[C:1]([C:4]1[CH:5]=[CH:6][C:7]([N:10]2[C:14]([CH3:15])=[C:13]3[C:16]([CH3:24])([C:21]([NH2:23])=[O:22])[CH2:17][C:18]([CH3:19])([CH3:20])[C:12]3=[C:11]2[CH3:25])=[CH:8][CH:9]=1)([O:3][CH3:26])=[O:2]

참가 물질

3

반응물 2

HCID 887MethanolHCID 234562082-(4-Carboxyphenyl)-2,4,5,6-tetrahydro-1,3,4,6,6-pentamethylcyclopenta[c]pyrrole-4-carboxamide

생성물 1

HCID 234561802-(4-Carbomethoxyphenyl)-2,4,5,6-tetrahydro-1,3,4,6,6-pentamethylcyclopenta[c]pyrrole-4-carboxamide

실험 절차

Reaction of the 2-(4-carboxyphenyl)-2,4,5,6-tetrahydro-1,3,4,6,6-pentamethylcyclopenta[c]pyrrole-4-carboxamide described above in Example 20BZ with methanol in the presence of a small amount of a mineral acid affords 2-(4-carbomethoxyphenyl)-2,4,5,6-tetrahydro-1,3,4,6,6-pentamethylcyclopenta[c]pyrrole-4-carboxamide.

출처 및 근거

ORD 기록
ord-a9fb77a768694aa08e6334c43cbca34d
출처 데이터셋
uspto-grants-1977_02
특허 번호
US04008250

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