Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diethyl Sulfate → N-[4-(diethylamino)-2-methylphenyl]acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diethyl Sulfate | HCID 6163 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 4-Acetamino-3-methyl-N-ethylaniline | HCID 21452831 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | N-[4-(diethylamino)-2-methylphenyl]acetamide | HCID 222177 | 64.4% |
반응 단계
19.1g (0.1 mole) of 4-acetamino-3-methyl-N-ethylaniline obtained in Example 1, Part C, and 100g of water were mixed, and, after 12.5g of diethyl sulfate were added dropwise thereto while stirring, the entire reaction system was stirred overnight at room temperature. Next, the reaction mixture was neutralized with sodium hydroxide and the crystals separated were recrystallized from methanol to obtain 11.5g of white crystals of 4-acetamino-3-methyl-(N,N-diethyl)aniline.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04009205 |
| 출처 데이터셋 | uspto-grants-1977_02 |
| ORD ID | ord-07f5cee7c9e849128dbff41ea39d7b24 |
| 출처 메모 | uspto-grants-1977_02 |