Pyridine → 3-Ethanesulphonyl-imidazolidin-2-on-1-carbonyl chloride

HRID 436624노트

반응식

HRID 436624 반응식
[CH2:1]([S:3]([N:6]1[CH2:10][CH2:9][NH:8][C:7]1=[O:11])(=[O:5])=[O:4])[CH3:2].[C:12](Cl)([Cl:14])=[O:13].N1C=CC=CC=1>ClCCl>[CH2:1]([S:3]([N:6]1[CH2:10][CH2:9][N:8]([C:12]([Cl:14])=[O:13])[C:7]1=[O:11])(=[O:5])=[O:4])[CH3:2]

참가 물질

5

반응물 3

HCID 1049PyridineHCID 6371PhosgeneHCID 112867961-Ethylsulphonyl-imidazolidin-2-one

생성물 1

HCID 117366063-Ethanesulphonyl-imidazolidin-2-on-1-carbonyl chloride

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

The N-ethanesulphonyl-imidazolidin-2-one was then suspended in dichloromethane, a large excess of phosgene was introduced at 0° C, a little pyridine was added and the mixture was left to stand overnight. The excess phosgene was then largely removed by passing in dry air and the product (3-ethanesulphonyl-imidazolidin-2-on-1-carbonyl chloride) was suspended in dichloromethane and filtered off.

후처리

  1. waitthe mixture was left
  2. customThe excess phosgene was then largely removed
  3. filtrationfiltered off

출처 및 근거

ORD 기록
ord-ce22aadcec354bc3a3d41232145be3cf
출처 데이터셋
uspto-grants-1977_02
특허 번호
US04009272

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