Cyclobutanone → 2-Cyclobutylnaphthalene

반응식

[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[Mg]Br.[C:13]1(=[O:17])[CH2:16][CH2:15][CH2:14]1>>[CH:13]1([C:2]2[CH:3]=[CH:4][C:5]3[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=3)[CH:1]=2)[CH2:16][CH2:15][CH2:14]1.[OH:17][C:13]1([C:2]2[CH:3]=[CH:4][C:5]3[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=3)[CH:1]=2)[CH2:16][CH2:15][CH2:14]1

참가 물질

반응물 2

HCID 14496Cyclobutanone

HCID 178418423HCID 178418423, 화합물

생성물 2

HCID 203350012-Cyclobutylnaphthalene

HCID 20335179Cyclobutanol, 1-(2-naphthalenyl)-

실험 절차

2-Cyclobutylnaphthalene is prepared from 2-naphthylmagnesium bromide by treating the latter with cyclobutanone to furnish 2-(1'-hydroxycyclobutyl)naphthalene, which is hydrogenolyzed with hydrogen in the presence of Raney nickel to furnish 2-cyclobutylnaphthalene.

출처 및 근거

ORD 기록: ord-a79730506b7e4c8b8d98822e5d1dffdf
출처 데이터셋: uspto-grants-1977_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04009197

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