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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 436782생성일: 2026년 10월 26일

1,3-Dibromo-2-propanone → 7-chloro-2-[[2-bromo-1-(bromomethyl)ethylidene]hydrazino]-5-(o-fluorophenyl)-3H-1,4-benzodiazepine

https://huagongshe.com/reaction/436782

반응식

참여 물질

역할이름HCID투입량
반응물1,3-Dibromo-2-propanoneHCID 69952—
반응물7-chloro-2-hydrazino-5-(o-fluorophenyl)-3H-1,4-benzodiazepineHCID 12390887—
용매TetrahydrofuranHCID 8028—
생성물7-chloro-2-[[2-bromo-1-(bromomethyl)ethylidene]hydrazino]-5-(o-fluorophenyl)-3H-1,4-benzodiazepineHCID 21431394—

반응 단계

In the manner given in Example 1, 7-chloro-2-hydrazino-5-(o-fluorophenyl)-3H-1,4-benzodiazepine in tetrahydrofuran can be treated with 1,3-dibromopropanone under nitrogen to give 7-chloro-2-[[2-bromo-1-(bromomethyl)ethylidene]hydrazino]-5-(o-fluorophenyl)-3H-1,4-benzodiazepine.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US04028356
출처 데이터셋uspto-grants-1977_06
ORD IDord-463a7a8ab7a2457c9ee7e5fcdcdbd439
출처 메모uspto-grants-1977_06