Hydride → Dinoprost

HRID 437096

반응식

[H-].[CH3:2][CH2:3][CH2:4][CH2:5][CH2:6][C@H:7]([OH:26])/[CH:8]=[CH:9]/[C@@H:10]1[C@@H:15]([CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][C:22]([OH:24])=[O:23])[C:13](=[O:14])[CH2:12][C@H:11]1[OH:25].[CH3:27][CH2:28][CH2:29][CH2:30][CH2:31][C@H:32]([OH:51])/[CH:33]=[CH:34]/[C@@H:35]1[C@@H:40]([CH2:41]/[CH:42]=[CH:43]\[CH2:44][CH2:45][CH2:46][C:47]([OH:49])=[O:48])[C:38](=[O:39])[CH2:37][C@H:36]1[OH:50]>>[CH3:2][CH2:3][CH2:4][CH2:5][CH2:6][C@H:7]([OH:26])/[CH:8]=[CH:9]/[C@@H:10]1[C@@H:15]([CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][C:22]([OH:24])=[O:23])[C@@H:13]([OH:14])[CH2:12][C@H:11]1[OH:25].[CH3:27][CH2:28][CH2:29][CH2:30][CH2:31][C@H:32]([OH:51])/[CH:33]=[CH:34]/[C@@H:35]1[C@@H:40]([CH2:41]/[CH:42]=[CH:43]\[CH2:44][CH2:45][CH2:46][C:47]([OH:49])=[O:48])[C@@H:38]([OH:39])[CH2:37][C@H:36]1[OH:50]

참가 물질

반응물 3

HCID 166653Hydride

HCID 5280360Prostaglandin E2

HCID 5280723Alprostadil

생성물 2

HCID 5280363Dinoprost

HCID 5280939PGF1alpha

실험 절차

Hydride reduction of the PGE1, PGE2, 11-desoxy-PGE1, and 11-desoxy-PGE2 analogues described in Sections B, C, and D, above, yield the corresponding PGF1, PGF2, 11-desoxy-PGF1 and 11-desoxy-PGF2 analogues, respectively:

출처 및 근거

ORD 기록: ord-8e3c83e5b50345ebbd123281074967bd
출처 데이터셋: uspto-grants-1977_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04029698

연결된 노트

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