Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-Pyridin-4-ylacetamide → 1-[2-(3,4-Dimethoxyphenyl)ethyl]-4-acetamidopyridinium iodide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-Pyridin-4-ylacetamide | HCID 21288 | — |
| 반응물 | 4-(2-Iodoethyl)-1,2-dimethoxybenzene | HCID 597022 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 1-[2-(3,4-Dimethoxyphenyl)ethyl]-4-acetamidopyridinium iodide | HCID 21413259 | 67.7% |
반응 단계
1-(2-Iodoethyl)-3,4-dimethoxybenzene (29.3 g.) and 4-acetamidopyridine (14.0 g.) in absolute ethanol (100 ml.) were refluxed for 2.5 hours. The resulting crystalline material was collectd and recrystallised from ethanol to give the title compound (29.1 g.), m.p. 201°-202° C. (Found: C, 47.9; H, 4.9; N, 6.3; C17H21IN2O3 requires C, 47.7; H, 4.9; N, 6.5%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04029801 |
| 출처 데이터셋 | uspto-grants-1977_06 |
| ORD ID | ord-12080977457145908188d689a8d8b499 |
| 출처 메모 | uspto-grants-1977_06 |