Triethylamine → 2-[2-(3-Chloro-2-ethylisoindol-1-yl)vinyl]-3-ethylbenzothiazolium perchlorate

HRID 437321

반응식

HRID 437321 반응식
[Cl:1]([O-:5])(=[O:4])(=[O:3])=[O:2].[Cl:6][C:7]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:9](=[CH:16]N(C)C)[N+:8]=1[CH2:20][CH3:21].C1(C)C=CC(S([O-])(=O)=O)=CC=1.[CH2:33]([N+:35]1[C:39]2[CH:40]=[CH:41][CH:42]=[CH:43][C:38]=2[S:37][C:36]=1[CH3:44])[CH3:34].C(N(CC)CC)C>C(#N)C>[Cl:1]([O-:5])(=[O:4])(=[O:3])=[O:2].[Cl:6][C:7]1[N:8]([CH2:20][CH3:21])[C:9]([CH:16]=[CH:44][C:36]2[S:37][C:38]3[CH:43]=[CH:42][CH:41]=[CH:40][C:39]=3[N+:35]=2[CH2:33][CH3:34])=[C:10]2[C:15]=1[CH:14]=[CH:13][CH:12]=[CH:11]2

참가 물질

5

반응물 3

HCID 8471TriethylamineHCID 84711Benzothiazolium, 3-ethyl-2-methyl-, 4-methylbenzenesulfonate (1:1)HCID 178462637HCID 178462637, 화합물

생성물 1

HCID 867348732-[2-(3-Chloro-2-ethylisoindol-1-yl)vinyl]-3-ethylbenzothiazolium perchlorate

시약·촉매·용매 1

HCID 6342Acetonitrile용매

실험 절차

3-chloro-1-dimethylaminomethylene-2-ethyl-1H-isoindolium perchlorate (0.5 g) and 3-ethyl-2-methylbenzothiazolium p-toluene sulfonate (0.5 g) were dissolved in acetonitrile and triethylamine added. After 30 minutes at room temperature the product was precipitated by the addition of ether and purified by chromatography on silica gel. After recrystalization from ethanol, the purified product melted at 244° C. CH3CN λ max 553 nm.

후처리

  1. customAfter 30 minutes at room temperature the product was precipitated by the addition of ether
  2. custompurified by chromatography on silica gel
  3. customAfter recrystalization from ethanol

출처 및 근거

ORD 기록
ord-13d3865f537c48a4a4becfb064f61741
출처 데이터셋
uspto-grants-1977_06
특허 번호
US04030932

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