Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Iodide → HCID 14810575, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Iodide | HCID 5238 | — |
| 반응물 | Butanoic acid, 4-chloro-, methyl ester | HCID 76612 | — |
| 반응물 | rel-(2R,6S)-2,6-Dimethylpiperidine | HCID 641768 | — |
| 용매 | O-Xylene | HCID 7237 | — |
| 생성물 | HCID 14810575 | HCID 14810575 | — |
반응 단계
A mixture of 273 g. of methyl 4-chlorobutyrate, 460 g. of cis-2,6-dimethylpiperidine, 10 g. of sodium iodide and 300 ml. of xylene is stirred and heated at reflux for 44 hours, then cooled and filtered. The filter cake is washed with xylene and the combined filtrate and washings are evaporated at reduced pressure to give cis-2,6-dimethyl-1-piperidinebutyric acid, methyl ester which is purified by distillation; b.p. 79°-81° C./0.5 mm.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04031101 |
| 출처 데이터셋 | uspto-grants-1977_06 |
| ORD ID | ord-d2f3b55717314692bbbb371b3e3261ff |
| 출처 메모 | uspto-grants-1977_06 |