Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Iodoethane → 5-Chloro-2-ethoxybenzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Iodoethane | HCID 6340 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 5-Chloro-2-hydroxybenzamide | HCID 348094 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 5-Chloro-2-ethoxybenzamide | HCID 20360293 | 36.6% |
반응 단계
A mixture of 5-chlorosalicylamide (16.0 g., 0.093 mole), iodoethane (31.8 g., 0.204 mole), and potassium carbonate (13.1 g., 0.095 mole) in ethanol (225 ml.) was heated under reflux for 20 hours. The hot mixture was filtered. The filtrate was reduced to dryness. The residue was triturated with water. The mixture was filtered and the collected solid recrystallized from acetonitrile to give 5-chloro-2-ethoxybenzamide (6.8 g., 36.6%) m.p. 136°-139°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04031093 |
| 출처 데이터셋 | uspto-grants-1977_06 |
| ORD ID | ord-a41ab30757f346f09213a2bfca4b3c19 |
| 출처 메모 | uspto-grants-1977_06 |