Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pinacolone → Methyl pivaloylacetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pinacolone | HCID 6416 | — |
| 반응물 | Dimethyl Carbonate | HCID 12021 | — |
| 반응물 | Sodium hydride | HCID 24758 | — |
| 용매 | Hexamethylphosphoramide | HCID 12679 | — |
| 생성물 | Methyl pivaloylacetate | HCID 99597 | 83.5% |
반응 단계
60 g of sodium hydride were suspended in 450 cc of dimethyl carbonate and 100 cc of hexamethyl phosphoric acid triamide. 100 g of pinacolone (92%) were added slowly at 45° C and on completion of the addition, the reaction mixture was processed as described in 3 above. The yield was 83.5% of pivaloyl acetic acid methyl ester.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04031130 |
| 출처 데이터셋 | uspto-grants-1977_06 |
| ORD ID | ord-0fb85a1d813f4f5ea5765711fed7dda6 |
| 출처 메모 | uspto-grants-1977_06 |