Ethyl Acetate → HCID 11148694, 화합물

HRID 437520노트

반응식

HRID 437520 반응식
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([NH:10][NH:11][C:12](=[O:17])[C:13]([F:16])([F:15])[F:14])=[CH:6][CH:5]=1)([O-])=O.C(OCC)(=O)C.[H][H]>C(O)C.[Pt]=O>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([NH:10][NH:11][C:12](=[O:17])[C:13]([F:14])([F:15])[F:16])=[CH:8][CH:9]=1

참가 물질

6

반응물 3

HCID 8857Ethyl AcetateHCID 31126762,2,2-trifluoro-N'-(4-nitrophenyl)acetohydrazideHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 11148694HCID 11148694, 화합물

시약·촉매·용매 2

HCID 82844Platinum oxide (PtO)촉매HCID 702Ethanol용매

실험 절차

2-(4-Nitrophenyl)-1-trifluoroacetylhydrazine (2.5 g, 0.01 mole) and platinum oxide (84%, catalytic amount) were mixed in ethanol (100 ml) and ethyl acetate (100 ml) in a Parr shaker bottle. The reaction mixture was hydrogenated at room temperature until hydrogen uptake ceased. The reaction mixture was filtered and the solvent was evaporated from the filtrate leaving a brown semisolid. Yield 2.0 g (91%), no m.p. was taken on this material. Spectral data verified its structure.

후처리

  1. filtrationThe reaction mixture was filtered
  2. customthe solvent was evaporated from the filtrate
  3. customleaving a brown semisolid

출처 및 근거

ORD 기록
ord-74e039caf05840cb80fe06a5c4baa469
출처 데이터셋
uspto-grants-1977_06
특허 번호
US04031127

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