Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Indoleglyoxylyl chloride → 1-(Indol-3-ylglyoxyloyl)-4-(p-fluorophenoxy)piperidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Indoleglyoxylyl chloride | HCID 89952 | — |
| 반응물 | 4-(4-Fluorophenoxy)piperidine | HCID 3734896 | — |
| 생성물 | 1-(Indol-3-ylglyoxyloyl)-4-(p-fluorophenoxy)piperidine | HCID 21428700 | — |
반응 단계
By following the manipulative procedure described in Example 4(b), 4-(p-fluorophenoxy)piperidine is reacted with indole-3-glyoxyloyl chloride to give 1-(indol-3-ylglyoxyloyl)-4-(p-fluorophenoxy)piperidine as an off-white solid. The solid is recrystallized twice from a methanol and water mixture to give white needles of the glyoxamide, m.p. 205°-207° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04031221 |
| 출처 데이터셋 | uspto-grants-1977_06 |
| ORD ID | ord-6a6ad0c756cf4b878f2a1ef7fb2e16d2 |
| 출처 메모 | uspto-grants-1977_06 |