Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl cis(+/-)-3-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)benzoate → Methyl cis(+/-)-3-(4-amino-3-methoxypiperidin-1-yl)benzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl cis(+/-)-3-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)benzoate | HCID 86648495 | — |
| 촉매 | HCID 178418390 | HCID 178418390 | — |
| 생성물 | Methyl cis(+/-)-3-(4-amino-3-methoxypiperidin-1-yl)benzoate | HCID 86648708 | 87.5% |
반응 단계
The same operation as in Example (160c) was performed using methyl cis(±)-3-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)benzoate obtained in Example (42a) (180 mg) and a 10% palladium-carbon catalyst (150 mg), to obtain 104.5 mg of the title compound as a white solid. The resulting compound was used for the next reaction without purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08536197B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-e4d7c9fea97e43ada9361d3a3512a57a |
| 출처 메모 | uspto-grants-2013_09 |