Phosgeniminium chloride → HCID 54107383, 화합물

HRID 437717

반응식

HRID 437717 반응식
[NH2:1][C:2]1[S:6][N:5]=[C:4]([C:7]([CH3:10])([CH3:9])[CH3:8])[C:3]=1[C:11]#[N:12].[Cl-].[Cl:14][C:15](Cl)=[N+:16]([CH3:18])[CH3:17]>ClCCl>[C:7]([C:4]1[C:3]([C:11]#[N:12])=[C:2]([N:1]=[C:15]([Cl:14])[N:16]([CH3:18])[CH3:17])[S:6][N:5]=1)([CH3:9])([CH3:8])[CH3:10]

참가 물질

4

반응물 2

HCID 2723945Phosgeniminium chlorideHCID 214267415-Amino-3-(1,1-dimethylethyl)-4-isothiazolecarbonitrile

생성물 1

HCID 54107383HCID 54107383, 화합물수율 67.7%

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

In the manner of Example VI, 9.1 g of 5-amino-3-tert-butyl- 4-cyanoisothiazole and 9.8 g of N-(dichloromethylene)-N,N-dimethylammonium chloride were allowed to react in 50 ml of dichloromethane. The volatile materials were evaporated under reduced pressure. The residue was recrystallized from hexane to give 9.2 g of N'-(3-tert-butyl-4 -cyano-5-isothiazolyl)-N,N-dimethylchloroformamidine, mp 94°-100°. The ir and nmr spectra were consistent with the assigned structures.

후처리

  1. customThe volatile materials were evaporated under reduced pressure
  2. customThe residue was recrystallized from hexane

출처 및 근거

ORD 기록
ord-1504d35d190a4cb181d6e756db393ccc
출처 데이터셋
uspto-grants-1977_06
특허 번호
US04032322

연결된 노트

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