Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diisopropylethylamine → Benzyl cis(+/-)-[3-methoxy-1-(6-methylpyrimidin-4-yl)piperidin-4-yl]carbamate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diisopropylethylamine | HCID 81531 | — |
| 반응물 | 4-Chloro-6-methylpyrimidine | HCID 581796 | — |
| 반응물 | Benzyl cis(+/-)-[3-methoxypiperidin-4-yl]carbamate hydrochloride | HCID 86648698 | — |
| 생성물 | Benzyl cis(+/-)-[3-methoxy-1-(6-methylpyrimidin-4-yl)piperidin-4-yl]carbamate | HCID 86648724 | — |
반응 단계
The same operation as in Example (158a) was performed using benzyl cis(±)-[3-methoxypiperidin-4-yl]carbamate hydrochloride obtained in Example (160a) (549 mg, 1.83 mmol), 4-chloro-6-methylpyrimidine (235 mg, 1.83 mmol) and diisopropylethylamine (709 mg, 5.48 mmol), to obtain the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08536197B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-2b22532a8c924b11bd7247ef9245e68d |
| 출처 메모 | uspto-grants-2013_09 |