Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Amino-3-hydroxybutanoic acid → N-(2,3,4,5,6-pentahydroxy-hexyl)-DL-threonine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Amino-3-hydroxybutanoic acid | HCID 205 | — |
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal | HCID 107526 | — |
| 촉매 | Nickel | HCID 935 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | N-(2,3,4,5,6-pentahydroxy-hexyl)-DL-threonine | HCID 21427714 | — |
반응 단계
The starting materials were D-glucose and DL-threonine. The reductive amination was carried out using Raney nickel or palladium/activated carbon (10%) and yielded a product having a melting point of 219° C. (decomposition) and a RF -value of 0.67 (determined on DC-finished plates of silica gel G (Merck) with a transporting fluid made up of 75 parts by volume of methanol and 25 parts by volume of water).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04032676 |
| 출처 데이터셋 | uspto-grants-1977_06 |
| ORD ID | ord-0045e3d370ba48e49958eaef34400e88 |
| 출처 메모 | uspto-grants-1977_06 |