Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → N-(5-carboxy-2,3,4,5-tetrahydroxy-pentyl)-L-(+)-glutamic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | L-Glutamic Acid | HCID 33032 | — |
| 반응물 | Glucuronic Acid | HCID 65041 | — |
| 촉매 | Nickel | HCID 935 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | N-(5-carboxy-2,3,4,5-tetrahydroxy-pentyl)-L-(+)-glutamic acid | HCID 54046356 | — |
반응 단계
As starting material D-glucuronic acid and L-(+)-glutamic acid were used. The reductive amination was carried out using Raney nickel as a catalyst and heating for 2 hours to 50° C. and for 4 hours to 70° C. The product obtained had a melting point of 90° C. (with sintering) an RF -value of 0.70 (determined on DC-finished plates of silica gel G (Merck) with a transporting liquid made up of 70 parts by volume of methanol and 30 parts by volume of water).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04032676 |
| 출처 데이터셋 | uspto-grants-1977_06 |
| ORD ID | ord-91fdf7bb5232460c8b88feb0fe6abf61 |
| 출처 메모 | uspto-grants-1977_06 |