Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzhydrylamine → cis(+/-)-1-(Diphenylmethyl)-2-ethylazetidin-3-ol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzhydrylamine | HCID 7036 | — |
| 반응물 | (2R*)-2-[(1S*)-1-bromopropyl]oxirane | HCID 86648818 | — |
| 생성물 | cis(+/-)-1-(Diphenylmethyl)-2-ethylazetidin-3-ol | HCID 10038631 | 29% |
반응 단계
The same operation as in Example (234b) was performed using (2R*)-2-[(1S*)-1-bromopropyl]oxirane obtained in Example (235a) (1.50 g, 9.09 mmol) and benzhydrylamine (1.57 mL, 9.09 mmol), to obtain 699 mg of the title compound as a pale yellow solid (29%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08536197B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-d3beea6e4def4d39ae80f2382e9a50cc |
| 출처 메모 | uspto-grants-2013_09 |