Piperazine → 1-Undecylpiperazine

HRID 439304

반응식

HRID 439304 반응식
[NH:1]1[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.Br[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]>ClCCl>[CH2:18]([N:1]1[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1)[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][CH3:8]

참가 물질

4

반응물 2

HCID 4837PiperazineHCID 127441-Bromoundecane

생성물 1

HCID 129309111-Undecylpiperazine

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

Excess piperazine (5 eq) and 1-bromoundecane (1.0 eq) are dissolved in dichloromethane and allowed to react overnight. The mixture is extracted with aqueous sodium bicarbonate and the organic layer dried with sodium sulfate. The mixture is filtered, the solvent removed in vacuo and the residue purified by column chromatography.

후처리

  1. customto react overnight
  2. extractionThe mixture is extracted with aqueous sodium bicarbonate
  3. dry with materialthe organic layer dried with sodium sulfate
  4. filtrationThe mixture is filtered
  5. customthe solvent removed in vacuo
  6. customthe residue purified by column chromatography

출처 및 근거

ORD 기록
ord-689265230eda49c3ab363bd8c0763242
출처 데이터셋
uspto-grants-1996_05
특허 번호
US05514651

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