Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → p-Methoxybenzamidoxime
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | Hydroxyamine hydrochloride | HCID 443297 | — |
| 반응물 | 4-[5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenol | HCID 135750113 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | p-Methoxybenzamidoxime | HCID 21471 | 20% |
반응 단계
3-(4-hydroxyphenyl)-5-trifluoromethyl-1,2,4-oxadiazole 13.32 g (0.1 mol) 4-methoxybenzonitrile, 20.85 g (0.3 mol) of hydroxylamine hydrochloride and 41.40 g (0.3 mol) potassium carbonate was added to 400 mL absolute ethanol and refluxed 21 hours. The product was filtered and recrystallized from methanol to give 3.12 g (0.02 mol) of 4-methoxybenzamide oxime.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05514679 |
| 출처 데이터셋 | uspto-grants-1996_05 |
| ORD ID | ord-ab3c90cfcdae41de9090a09db9c42a50 |
| 출처 메모 | uspto-grants-1996_05 |