Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(4-Phenyl-4-n-propyl-4-silacyclohexyl)cyclohexanone → 4-(4-(4-Fluorophenyl)-3-cyclohexenyl)-1-phenyl-1-n-propyl-1-silacyclohexane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(4-Phenyl-4-n-propyl-4-silacyclohexyl)cyclohexanone | HCID 11034390 | — |
| 반응물 | HCID 178505844 | HCID 178505844 | — |
| 생성물 | 4-(4-(4-Fluorophenyl)-3-cyclohexenyl)-1-phenyl-1-n-propyl-1-silacyclohexane | HCID 11014694 | 82% |
반응 단계
In the same manner as in Example 1, 35.0 g of 4-(4-n-propyl-4-phenyl-4-silacyclohexyl)cyclohexanone were subjected to coupling reaction with 4-fluorophenylmagnesium chloride, followed by dehydration reaction in the presence of an acid catalyst to obtain 35.9 g of 4-(4-n-propyl-4-phenyl-4-silacyclohexyl)-1-(4-fluorophenyl)-1-cyclohexene (yield: 82%). The results of 1H-NMR analysis are shown below. 1H-NMR (CDCl3) δ:0.50-2.55 (23H, m), 5.90-6.14 (1H, m), 6.80-7.65 (9H, ppm
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05514824 |
| 출처 데이터셋 | uspto-grants-1996_05 |
| ORD ID | ord-c1ad0bce64464ad4b2e00e75591c42e0 |
| 출처 메모 | uspto-grants-1996_05 |