Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pentafluorobenzyl bromide → HCID 88371353, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pentafluorobenzyl bromide | HCID 74484 | — |
| 반응물 | 3',5'-Dihydroxyacetophenone | HCID 103993 | — |
| 생성물 | HCID 88371353 | HCID 88371353 | 98% |
반응 단계
Synthesized by 1:2 ratio of 3',5'-dihydroxyacetophenone to pentafluorobenzyl bromide. Yield: 98%. m.p. 102°-103° C. 1H NMR, δ: 2.60 (s, 3H, CH3CO), 5.22 (s, 4H, CH2O), 6.83 (bs, 1H, H-C4'), 7.24 (d, 2H, J=1.8 Hz, H-C2' & H-C6') ppm; 13C NMR, δ: 26.0 (CH3CO), 57.4 (CH2O), 106.4 (C4'), 107.4 (C2' & C6'), 109.7 (C1", 2JC-F =17 Hz) 137.4 (C2" & C6", JC-F =249 Hz), 139.2 (C1'), 141.7 (C4", JC-F =256 Hz), 145.7 (C3" & C5", JC-F =251 Hz), 159.2 (C3' & C5'), 196.7 (C=O) ppm. MS (EI): 331 ([M-PFBz]+); MS (ECNI): 331 ([M-PFBz]-, 100%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05516931 |
| 출처 데이터셋 | uspto-grants-1996_05 |
| ORD ID | ord-855b77e8c7314295a9fbd30cb6ae6ac8 |
| 출처 메모 | uspto-grants-1996_05 |