Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(3-Nitropyridin-2-yl)piperazine → 2-(Piperazin-1-yl)pyridin-3-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(3-Nitropyridin-2-yl)piperazine | HCID 3778834 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | HCID 178418390 | HCID 178418390 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 2-(Piperazin-1-yl)pyridin-3-amine | HCID 10397358 | 95.8% |
반응 단계
In 30 ml of methanol was dissolved 3.13 g (0.015 mole) of 1-(3-nitro-2-pyridyl)piperazine, and 2 g of 5% palladium carbon was added thereto. While stirring the mixture at room temperature, hydrogen gas was passed through for one hour. The reaction mixture was filtered, and the filtrate was concentrated under reduced pressure to obtain 2.56 g of 1-(3-amino-2-pyridyl)piperazine as pale yellow liquid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05519016 |
| 출처 데이터셋 | uspto-grants-1996_05 |
| ORD ID | ord-ddd5187149e74fe9b7a86c02188a48f5 |
| 출처 메모 | uspto-grants-1996_05 |