참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Hydrogen Bromide | HCID 260 | — |
| 반응물 | Diethyl Ether | HCID 3283 | — |
| 반응물 | Phenyl acridine-9-carboxylate | HCID 517916 | — |
| 반응물 | Tert-butyl 2-iodoacetate | HCID 11021060 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 9-Phenoxycarbonyl-10-carboxymethylacridinium bromide | HCID 19364939 | — |
반응 단계
A mixture of phenyl acridine-9-carboxylate (100 mg) and t-butyl iodoacetate is stirred and heated at 110° C. for five hours. The resulting solution is poured into diethyl ether (25 ml) and the resulting precipitate isolated by filtration. Part of this precipitate (10 mg) is stirred with 33% hydrobromic acid in acetic acid (1 ml), and heated at 50° C. for two hours. The reaction mixture is poured into water, and the resulting precipitate (ca. 6 mg) isolated. MS: 358, 314, 300, 237, 220, 206.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05521103 |
|---|
| 출처 데이터셋 | uspto-grants-1996_05 |
|---|
| ORD ID | ord-ff48499828724ea1af2ccfe2d7352e58 |
|---|
| 출처 메모 | uspto-grants-1996_05 |
|---|
