Butylamine → HCID 135623124, 화합물

반응식

[OH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8](=O)[CH2:9][S:10]([CH3:12])=[O:11].[CH2:14]([NH2:18])[CH2:15][CH2:16][CH3:17]>>[CH2:14]([N:18]=[C:8]([C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[OH:1])[CH2:9][S:10]([CH3:12])=[O:11])[CH2:15][CH2:16][CH3:17]

참가 물질

반응물 2

HCID 8007Butylamine

HCID 578088HCID 578088, 화합물

생성물 1

HCID 135623124HCID 135623124, 화합물수율 95%

실험 절차

A solution of 2'-hydroxy-2-(methylsulfinyl)acetophenone (15 g, 0.076 mole) in n-butylamine (75 ml) was stirred at room temperature for 16 hrs. The reaction mixture was poured into petroleum ether (500 ml) and the product, which precipitated, was filtered off. Recrystallization from ethylacetate-cyclohexane gave yellow crystals (18.2 g, 95%), mp 128°-129°.

후처리

customthe product, which precipitated
filtrationwas filtered off
customRecrystallization from ethylacetate-cyclohexane

출처 및 근거

ORD 기록: ord-84792e350263417ba3a2869b3efb6861
출처 데이터셋: uspto-grants-1977_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04039579

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