2-[(4-Methylphenyl)amino]acetic acid → 2-(Cyclopentylamino)acetamide

반응식

C[C:2]1[CH:7]=[CH:6][C:5]([NH:8][CH2:9][C:10]([OH:12])=O)=[CH:4]C=1.C1([NH:18]CC(O)=O)CCCC1>>[CH:5]1([NH:8][CH2:9][C:10]([NH2:18])=[O:12])[CH2:4][CH2:2][CH2:7][CH2:6]1

참가 물질

반응물 2

HCID 2422362-[(4-Methylphenyl)amino]acetic acid

HCID 3141012-(Cyclopentylamino)acetic acid

생성물 1

HCID 167782572-(Cyclopentylamino)acetamide

실험 절차

By replacing the p-methylphenylglycine employed in Procedure 14, Step A by an equivalent quantity of cyclopentylglycine, there is obtained cyclopentylglycinamide. Substituting this cyclopentylglycinamide for that employed in Procedure 13 and following the methods described in Steps A and B of Procedure 13, there is obtained in Step A 2-hydroxy-3-cyclopentylpyrazine and in Step B 2-chloro-3-cyclopentylpyrazine.

출처 및 근거

ORD 기록: ord-c0e36ea2753c4802b4d05f647842a072
출처 데이터셋: uspto-grants-1977_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04042586

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