1-Iodo-3-nitrobenzene → 5-Methyl-1-(3-nitrophenyl) pyridone

반응식

I[C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([N+:8]([O-:10])=[O:9])[CH:3]=1.[CH3:11][C:12]1[CH:13]=[CH:14][C:15](=[O:18])[NH:16][CH:17]=1>>[CH3:11][C:12]1[CH:13]=[CH:14][C:15](=[O:18])[N:16]([C:2]2[CH:7]=[CH:6][CH:5]=[C:4]([N+:8]([O-:10])=[O:9])[CH:3]=2)[CH:17]=1

참가 물질

반응물 2

HCID 125741-Iodo-3-nitrobenzene

HCID 704822-Hydroxy-5-methylpyridine

생성물 1

HCID 98375125-Methyl-1-(3-nitrophenyl) pyridone수율 75%

실험 절차

The reaction of 24.9 g of 1-iodo-3-nitrobenzene (Aldrich Chemical Co.) with 10.9 of 5-methyl-2-(1H)-pyridone by the procedure described in Example 1 affords 16.2g (75%) of 5-methyl-1-(3-nitro-phenyl) pyridone.

출처 및 근거

ORD 기록: ord-2479917f5f304c738deb7df7841dc71c
출처 데이터셋: uspto-grants-1977_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04042699

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