Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
6-Phenyl-2-pyridone → Z-Val-Val-OMe
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 6-Phenyl-2-pyridone | HCID 87889 | — |
| 반응물 | Sodium | HCID 5360545 | — |
| 반응물 | 6-Hydroxynicotinonitrile | HCID 7062197 | — |
| 반응물 | HCID 178493244 | HCID 178493244 | — |
| 반응물 | 6-(2-Phenylethyl)pyridin-2(1h)-one | HCID 178516001 | — |
| 반응물 | HCID 178516071 | HCID 178516071 | — |
| 반응물 | HCID 178517620 | HCID 178517620 | — |
| 생성물 | Z-Val-Val-OMe | HCID 12286262 | — |
반응 단계
When the sodium salt of 6-n-amyl-2-hydroxypyridine, 5-cyano-2-hydroxypyridine, 2-hydroxy-4-methoxypyridine, 2-hydroxy-6-phenylpyridine, 2-hydroxy-6-phenethylpyridine or 1-hydroxyisoquinoline is used in place of the sodium salt of 2-hydroxypyridine, the yields of benzyloxycarbonyl-L-valyl-L-valine methyl ester are 72, 83, 81, 76, 80 and 73%, respectively.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04043992 |
| 출처 데이터셋 | uspto-grants-1977_08 |
| ORD ID | ord-ac132a5111bf4aa0895a31dfe88cfe61 |
| 출처 메모 | uspto-grants-1977_08 |