Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
7-Methoxy-1,2,3,4-Tetrahydroisoquinoline → 4-Amino-2-(7-methoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)-6,7,8-trimethoxyquinazoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 7-Methoxy-1,2,3,4-Tetrahydroisoquinoline | HCID 417288 | — |
| 반응물 | 2-Chloro-6,7,8-trimethoxyquinazolin-4-amine | HCID 3015804 | — |
| 생성물 | 4-Amino-2-(7-methoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)-6,7,8-trimethoxyquinazoline | HCID 21416727 | — |
반응 단계
The procedure described in Example 1 was followed to prepare the above compound, starting from 4-amino-2-chloro-6,7,8-trimethoxyquinazoline and using 7-methoxy-1,2,3,4-tetrahydroisoquinoline as the reagent of choice on the same molar basis as before. In this particular case, the final product was isolated as the hydrochloride salt m.p. 236° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04044136 |
| 출처 데이터셋 | uspto-grants-1977_08 |
| ORD ID | ord-55995c372d37476ea5a75eadd7f11775 |
| 출처 메모 | uspto-grants-1977_08 |