Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trichloroacetyl chloride → 2-(Trichloroacetyl)pyrrole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trichloroacetyl chloride | HCID 6420 | — |
| 반응물 | Pyrrole | HCID 8027 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | 2-(Trichloroacetyl)pyrrole | HCID 321487 | — |
반응 단계
To a solution of trichloroacetyl chloride (160.7 mmoles) in ethyl ether (26 ml) there is added, dropwise over a period of 3 hours, a solution of pyrrole (149 mmoles) in ethyl ether (83 ml). After stirring for a further hour, a solution of potassium carbonate (94 mmoles) in water (39 ml) is added dropwise. The phases are separated and the organic phase is dried over sodium sulphate and filtered. Active carbon is added to this organic phase. After stirring for 5 minutes, the organic phase is filtered and evaporated to dryness to yield the title product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08541412B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-c606efcc6d174fd5af17b1eca1f8b113 |
| 출처 메모 | uspto-grants-2013_09 |