Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 4'-Nonanoyloxybiphenyl-4-carboxylic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 2-Dimethylaminopyridine | HCID 21885 | — |
| 반응물 | Nonanoyl chloride | HCID 69819 | — |
| 반응물 | 4'-Hydroxy-4-biphenylcarboxylic acid | HCID 301556 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 용매 | Triethylamine | HCID 8471 | — |
| 생성물 | 4'-Nonanoyloxybiphenyl-4-carboxylic acid | HCID 13668451 | 86.3% |
반응 단계
4'-Hydroxybiphenyl-4-carboxylic acid (3.5 g) and triethylamine (2.4 g) were dissolved in dichloromethane (30 ml). Nonanoyl chloride (4.3 g) and dimethylaminopyridine (0.2 g) were added to the solution, and the mixture was stirred at room temperature for about 20 hours. Dilute hydrochloric acid was added thereto, and the organic layer was separated in a separating funnel. The solvent was removed by evaportaion, and the residue was dried after washing with n-hexane to give the titled compound (5 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05891359 |
| 출처 데이터셋 | uspto-grants-1999_04 |
| ORD ID | ord-0fbb1e06db2441929e7b81c2113f4d94 |
| 출처 메모 | uspto-grants-1999_04 |