2,6-Dichlorobenzaldehyde → (3Z)-1-acetyl-3-(2,6-dichlorobenzylidene)-2,5-piperazinedione
반응식
C([N:4]1[CH2:9][C:8](=[O:10])[N:7]([C:11](=[O:13])[CH3:12])[CH2:6][C:5]1=[O:14])(=O)C.[Cl:15][C:16]1[CH:23]=[CH:22][CH:21]=[C:20]([Cl:24])[C:17]=1[CH:18]=O.C(N(CC)CC)C>CN(C=O)C>[C:11]([N:7]1[CH2:6][C:5](=[O:14])[NH:4]/[C:9](=[CH:18]\[C:17]2[C:16]([Cl:15])=[CH:23][CH:22]=[CH:21][C:20]=2[Cl:24])/[C:8]1=[O:10])(=[O:13])[CH3:12]참가 물질
5
실험 절차
1,4-Diacetyl-2,5-piperazinedione prepared by the published procedure mentioned in Reference Example 3, was stirred in DMF with 2,6-dichlorobenzaldehyde and triethylamine and heated to 120°-130° C. for 1-3 h. The title compound was obtained with a yield of 40%.
후처리
- temperatureheated to 120°-130° C. for 1-3 h
출처 및 근거
- ORD 기록
- ord-580416b22eb44c648a525512ce786adc
- 출처 데이터셋
- uspto-grants-1999_04
- 특허 번호
- US05891877
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