Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phosphorus oxide (P4O10) → Methyl 4,5-Methylenedioxy-2-(3-methyl-4-nitrobenzoyl)phenylacetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phosphorus oxide (P4O10) | HCID 14812 | — |
| 반응물 | 3-Methyl-4-nitrobenzoic acid | HCID 18370 | — |
| 반응물 | Methyl 2-(1,3-dioxaindan-5-yl)acetate | HCID 266588 | — |
| 용매 | 1,2-Dichloroethane | HCID 11 | — |
| 생성물 | Methyl 4,5-Methylenedioxy-2-(3-methyl-4-nitrobenzoyl)phenylacetate | HCID 53912114 | — |
반응 단계
The title compound was prepared from methyl 3,4-methylenedioxyphenylacetate (2.1 g, 11 mmol) in ClCH2CH2Cl (70 mL), 3-methyl-4-nitrobenzoic acid (3.7 g, 20 mmol) and P2O5 (6 g) as an oily solid (1.4 g, 3.9 mmol, 35%). 1H NMR (CDCl3) 7.99 (d, J=8.2, 1H), 7.74 (s, 1H), 6.69 (d, J=8.2, 1H), 6.84 (s, 1H), 6.83 (s, 1H), 6.07 (s, 2H), 3.86 (s, 2H), 3.64 (s, 3H), 2.63 (s, 3H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05891871 |
| 출처 데이터셋 | uspto-grants-1999_04 |
| ORD ID | ord-40d6e34c8e0a41b88484cf648bb50b89 |
| 출처 메모 | uspto-grants-1999_04 |