Xanthydrol → ethyl 2-(4-bromobenzoyl)-2-(9H-xanthen-9-yl)acetate

HRID 442806

반응식

HRID 442806 반응식
[Br:1][C:2]1[CH:15]=[CH:14][C:5]([C:6]([CH2:8][C:9]([O:11][CH2:12][CH3:13])=[O:10])=[O:7])=[CH:4][CH:3]=1.O[CH:17]1[C:30]2[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=2[O:24][C:23]2[C:18]1=[CH:19][CH:20]=[CH:21][CH:22]=2>C(O)C.C(O)(=O)C>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]([CH:8]([CH:17]2[C:18]3[CH:19]=[CH:20][CH:21]=[CH:22][C:23]=3[O:24][C:25]3[C:30]2=[CH:29][CH:28]=[CH:27][CH:26]=3)[C:9]([O:11][CH2:12][CH3:13])=[O:10])=[O:7])=[CH:14][CH:15]=1

참가 물질

4

반응물 2

HCID 72861XanthydrolHCID 2757149Ethyl 3-(4-bromophenyl)-3-oxopropanoate

생성물 1

HCID 54346958ethyl 2-(4-bromobenzoyl)-2-(9H-xanthen-9-yl)acetate

시약·촉매·용매 1

HCID 18476134Acetic acid ethanol용매

실험 절차

A solution of ethyl 4-bromobenzoylacetate (14.8 g, 0.05 mol) and 9-hydroxyxanthene (10.9 g, 0.06 mol) in ethanol-acetic acid (1:1, 150 ml) was stirred as described in Example 3 (ii) and a white solid collected. The filtrate was stirred a further 3 days and a second crop collected to give ethyl 2-(4-bromobenzoyl)-2-(9H-xanthen-9-yl)acetate.

후처리

  1. customa white solid collected
  2. customa second crop collected

출처 및 근거

ORD 기록
ord-92a9a86fea05419a997585619bb98cbc
출처 데이터셋
uspto-grants-1999_04
특허 번호
US05891899

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