4-Hydroxy-3,5-bis(isopropyl)benzaldehyde → (E)-2-(Benzylaminosulfonyl)-3-(3,5-diisopropyl-4-hydroxyphenyl)acrylonitrile

반응식

[CH:1]([C:4]1[CH:5]=[C:6]([CH:9]=[C:10]([CH:13]([CH3:15])[CH3:14])[C:11]=1[OH:12])[CH:7]=O)([CH3:3])[CH3:2].[CH2:16]([NH:23][S:24]([CH2:27][C:28]#[N:29])(=[O:26])=[O:25])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[CH2:16]([NH:23][S:24](/[C:27](=[CH:7]/[C:6]1[CH:5]=[C:4]([CH:1]([CH3:3])[CH3:2])[C:11]([OH:12])=[C:10]([CH:13]([CH3:15])[CH3:14])[CH:9]=1)/[C:28]#[N:29])(=[O:26])=[O:25])[C:17]1[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=1

참가 물질

반응물 2

HCID 827124-Hydroxy-3,5-bis(isopropyl)benzaldehyde

HCID 15410493HCID 15410493, 화합물

생성물 1

HCID 18185617(E)-2-(Benzylaminosulfonyl)-3-(3,5-diisopropyl-4-hydroxyphenyl)acrylonitrile

실험 절차

The titled compound was prepared with 3,5-diisopropyl-4-hydroxybenzaldehyde and N-benzyl cyanomethylsulfonamide under the similar conditions as described for EXAMPLE 12 (part B).

출처 및 근거

ORD 기록: ord-29946cebef504a85bde2e90ceb1d766f
출처 데이터셋: uspto-grants-1999_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05891917

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