참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Ethanolamine | HCID 700 | — |
| 반응물 | 4-Nitrophenethyl bromide | HCID 79266 | — |
| 생성물 | 2-[2-(4-Nitro-phenyl)-ethylamino]-ethanol | HCID 22722744 | — |
반응 단계
A mixture of 1-(2-bromo-ethyl)-4-nitro-benzene (86.9 mmoles) and 2-amino-ethanol (869 mmoles) is heated at 150° C. under microwave activation for 10 minutes. The reaction mixture is evaporated to dryness and the residue obtained is purified on silica gel (SiO2; gradient DCM/MeOH) to yield the title product, which is used directly in the next Step.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08541412B2 |
|---|
| 출처 데이터셋 | uspto-grants-2013_09 |
|---|
| ORD ID | ord-2b4fbf189855456f819977f42058ce7e |
|---|
| 출처 메모 | uspto-grants-2013_09 |
|---|
