Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl iodide → 2-Methoxy-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl iodide | HCID 6328 | — |
| 반응물 | N-(3-cyano-4,5-dimethylthiophen-2-ylcarbamoyl)benzamide | HCID 57456902 | — |
| 생성물 | 2-Methoxy-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine | HCID 25224339 | 86% |
반응 단계
Prepared in a similar manner to Example 25 from N-(3-cyano-4,5-dimethylthiophen-2-ylcarbamoyl)benzamide (Example 4a) and methyl iodide in 86% yield. 1H NMR (400 MHz, CDCl3) δ2.35 (s, 3H), 2.36 (s, 3H), 3.53 (s, 3H), 6.0 (bs, 2H). MS 210 (MH+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08541421B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-999165459808454a92efc7421d31629e |
| 출처 메모 | uspto-grants-2013_09 |