참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 2-Methylpyridine-3-carbonitrile | HCID 4738308 | — |
| 반응물 | 2-(Phenylmethyl)-3-pyridinecarbonitrile | HCID 12428725 | — |
| 반응물 | 3-Cyano-2-phenethylpyridine | HCID 12428728 | — |
| 반응물 | 2-Ethylnicotinonitrile | HCID 15454017 | — |
| 생성물 | 1-Amino-3-methyl-4-phenyl-2,5-naphthyridine | HCID 23467600 | — |
| 생성물 | 1-Amino-3,4-dimethyl-2,5-naphthyridine | HCID 23467654 | — |
| 생성물 | 1-Amino-3-methyl-4-benzyl-2,5-naphthyridine | HCID 23467667 | — |
반응 단계
Similarly, by substituting the 3-cyano-2-methylpyridine reactant with equivalent quantities of 3-cyano-2-ethylpyridine, 3-cyano-2-benzylpyridine, 3-cyano-2-phenethylpyridine and by substantially following the foregoing reaction procedure there is produced 1-amino-3,4-dimethyl-2,5-naphthyridine, 1-amino-3-methyl-4-phenyl-2,5-naphthyridine, 1-amino-3-methyl-4-benzyl-2,5-naphthyridine, respectively. Similarly, in each of those reactions wherein the 3-cyano-2-methylpyridine has been substituted with another 3-cyano-2-substituted pyridine the acetonitrile reactant may also be substituted with the aforementioned nitriles and by substantially following the procedure described in the example, there is produced the appropriate 1-amino-3- and 4-substituted, 2,5-naphthyridines.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04260759 |
|---|
| 출처 데이터셋 | uspto-grants-1981_04 |
|---|
| ORD ID | ord-1d4e03c07bf3403bb221b4a17d314080 |
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| 출처 메모 | uspto-grants-1981_04 |
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