Thionyl Chloride → 2,2-Dichloro-1-(4-ethoxyphenyl)cyclopropane-1-carbonyl chloride

HRID 443927노트

반응식

HRID 443927 반응식
[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]2([C:15]([OH:17])=O)[CH2:12][C:11]2([Cl:14])[Cl:13])=[CH:6][CH:5]=1)[CH3:2].S(Cl)([Cl:20])=O>>[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]2([C:15]([Cl:20])=[O:17])[CH2:12][C:11]2([Cl:14])[Cl:13])=[CH:6][CH:5]=1)[CH3:2]

참가 물질

3

반응물 2

HCID 24386Thionyl ChlorideHCID 135804022,2-Dichloro-1-(4-ethoxyphenyl)cyclopropane-1-carboxylic acid

생성물 1

HCID 130410812,2-Dichloro-1-(4-ethoxyphenyl)cyclopropane-1-carbonyl chloride

실험 절차

The 1-p-ethoxyphenyl-2,2-dichlorocyclopropane-1-carboxylic acid (1.38 g) was refluxed on a water bath with thionyl chloride (1.19 g) for 15 minutes. The excess thionyl chloride was then evaporated under vacuum (1 Torr.) and the residue of carbonyl chloride reacted without further purification with one of the alcohols (a), (b), (c) or (d). ##STR9##

후처리

  1. customThe excess thionyl chloride was then evaporated under vacuum (1 Torr.)
  2. customthe residue of carbonyl chloride reacted without further purification with one of the alcohols (a), (b), (c) or (d)

출처 및 근거

ORD 기록
ord-cdecd38325f9419bb0386d5b9c98dac9
출처 데이터셋
uspto-grants-1981_04
특허 번호
US04262014

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