Methyl fluorosulfate → 3-Benzyloxy-2-methylisothiazolium fluorosulfonate

HRID 443992노트

반응식

[CH2:1]([O:8][C:9]1[CH:13]=[CH:12][S:11][N:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[F:14][S:15]([O:18][CH3:19])(=[O:17])=[O:16]>>[F:14][S:15]([O-:18])(=[O:17])=[O:16].[CH2:1]([O:8][C:9]1[CH:13]=[CH:12][S:11][N+:10]=1[CH3:19])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

참가 물질

반응물 2

HCID 9870Methyl fluorosulfate

HCID 111831203-Benzyloxyisothiazole

생성물 1

HCID 867376963-Benzyloxy-2-methylisothiazolium fluorosulfonate수율 90%

실험 절차

3-Benzyloxyisothiazole (3.0 g, 0.016 mol) and 5 ml of methyl fluorosulfonate were heated at 60° for 30 min. After cooling, the solid was washed with ether to yield 4.3 g (90%) of 3-benzyloxy-2-methylisothiazolium fluorosulfonate, mp 75°-78° C. (d).

후처리

temperatureAfter cooling
washthe solid was washed with ether

출처 및 근거

ORD 기록: ord-694570ea7a62452b888911aed976a17d
출처 데이터셋: uspto-grants-1981_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04262127

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