Cyanic acid → 5-(6-Ethoxycarbonylhexyl)-1-(3-cyclohexyl-3-oxopropyl)hydantoin
반응식
[CH:1]1([C:7](=[O:28])[CH2:8][CH2:9][NH:10][CH:11]([CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][C:23]([O:25][CH2:26][CH3:27])=[O:24])[C:12]([O:14]CC)=O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[N:29]#[C:30][OH:31]>>[CH2:26]([O:25][C:23]([CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH:11]1[N:10]([CH2:9][CH2:8][C:7]([CH:1]2[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]2)=[O:28])[C:30](=[O:31])[NH:29][C:12]1=[O:14])=[O:24])[CH3:27]참가 물질
3
실험 절차
Reaction of diethyl 2-((3-cyclohexyl-3-oxopropyl)amino)nonanedioate (20.8 g) with cyanic acid using the general procedure of Example 2d afforded 5-(6-ethoxycarbonylhexyl)-1-(3-cyclohexyl-3-oxopropyl)hydantoin which was converted to the corresponding acid which crystallised from ether, m.p. 77.5°-78.5° C.
출처 및 근거
- ORD 기록
- ord-ae1f242a9584414e9c067da8f621213a
- 출처 데이터셋
- uspto-grants-1981_04
- 특허 번호
- US04262128