m-Chloroperbenzoic acid → Methyl 10,11-Dihydro-11-oxodibenzo[b,f][1,4]thiazepin-7-carboxylate 5-Oxide
반응식
[O:1]=[C:2]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[S:6][C:5]2[CH:13]=[C:14]([C:17]([O:19][CH3:20])=[O:18])[CH:15]=[CH:16][C:4]=2[NH:3]1.ClC1C=CC=C(C(OO)=[O:29])C=1>C(Cl)Cl>[O:1]=[C:2]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[S:6](=[O:29])[C:5]2[CH:13]=[C:14]([C:17]([O:19][CH3:20])=[O:18])[CH:15]=[CH:16][C:4]=2[NH:3]1참가 물질
4
실험 절차
Suspend 1.14 gm (4 mmole) of the ester of Example 23 in 60 ml of methylene chloride and add 1.035 gm of commercial m-chloroperbenzoic acid. Stir at room temperature for 45 minutes and filter. Concentrate the filtrate and separate the solids. Combine the solids to obtain the title product (yield 1.21 gm).
후처리
- filtrationfilter
- concentrationConcentrate the filtrate
- customseparate the solids
출처 및 근거
- ORD 기록
- ord-54d9c542f7084a84a29c8219ea8a8dcd
- 출처 데이터셋
- uspto-grants-1981_04
- 특허 번호
- US04263207
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