Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acefylline → N-[2-(4-Cyanophenyl)-ethyl]-2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-purin-7-yl)acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acefylline | HCID 69550 | — |
| 반응물 | 4-(2-Aminoethyl)benzonitrile | HCID 21912525 | — |
| 생성물 | N-[2-(4-Cyanophenyl)-ethyl]-2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-purin-7-yl)acetamide | HCID 59205118 | 21.2% |
반응 단계
Compound 409 (93 mg, 21%) was prepared from 101 (300 mg, 1.3 mmol) and 115 (175 mg, 1.2 mmol) according to General Procedure B. MS (APCI): m/z 367 [M+H]+. Anal. Calcd. for C18H18N6O3.0.04EtOAc.0.1H2O: C, 58.68; H, 5.02; N, 22.61. Found: C, 58.75; H, 5.01; N, 22.46.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08541423B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-043c58e87eac4d25821711ff7f9377e9 |
| 출처 메모 | uspto-grants-2013_09 |