Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3'-Aminoacetophenone → N-(3-acetylphenyl)hexadecane-1-sulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3'-Aminoacetophenone | HCID 7417 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | 1-Hexadecanesulfonyl chloride | HCID 96923 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | N-(3-acetylphenyl)hexadecane-1-sulfonamide | HCID 23464850 | — |
반응 단계
To a mechanically stirred solution of 31.2 g (0.23 M) of m-aminoacetophenone and 35.4 ml (0.254 M) of triethylamine in 1 liter of tetrahydrofuran was added 75 g (0.23 M) of 1-hexadecanesulfonyl chloride at room temperature. The mixture was stirred for 2 hours and the suspended salt was removed. The filtrate was treated on a rotary evaporator to give a solid which was recrystallized from hexane: mp 95.5°-100° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04263393 |
| 출처 데이터셋 | uspto-grants-1981_04 |
| ORD ID | ord-c9d2c608a7bc41c1ada858e58a2807da |
| 출처 메모 | uspto-grants-1981_04 |