Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 44482생성일: 2026년 10월 23일
Potassium Carbonate → 6-bromo-2-(1-methylethyl)-1-(1-naphthalenylmethyl)-4-nitro-1H-benzimidazole
https://huagongshe.com/ko/reaction/44482
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 1-(Bromomethyl)naphthalene | HCID 137844 | — |
| 반응물 | 6-bromo-2-isopropyl-4-nitro-1H-benzo[d]imidazole | HCID 66976725 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 6-bromo-2-(1-methylethyl)-1-(1-naphthalenylmethyl)-4-nitro-1H-benzimidazole | HCID 66976896 | 102.6% |
반응 단계
A mixture of 6-bromo-2-isopropyl-4-nitro-1H-benzo[d]imidazole (4.7 g), 1-(bromomethyl)naphthalene (4.01 g) and K2CO3 (4.55 g) in DMF (150 mL) was stirred at 80° C. for 2 h. It was cooled to room temperature and filtered. The filtrate was then poured into water (1 L). It was then filtered to afford a solid that was washed with water and then dried in-vacuo to afford the crude product (7.2 g). LC-MS: m/e=425 [M+1]+
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US08541411B2 |
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| 출처 데이터셋 | uspto-grants-2013_09 |
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| ORD ID | ord-652cf95ec8b94d8c811f7498dd9f7fb1 |
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| 출처 메모 | uspto-grants-2013_09 |
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